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Sleep and the Immune System: Why Sleep Is Key to Staying Healthy
There’s a reason why it’s easier to catch a cold if you don’t catch enough ZZZs. Study after study shows that being sick and being tired go hand in hand!

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Dr. Harvey Karp

There’s a reason why “sick and tired” just rolls off the tongue—study after study shows that being sick and being tired go hand in hand. Think of exhaustion and illness like some diabolical duo, a Bonnie and Clyde-style assault on your immune system!
Getting sleep helps the body protect itself against infection. Likewise, being sleep deprived can weaken our immune defenses. You don’t feel on your A-game when you’re pooped…and, similarly, your immune system is struggling when you’re struggling to keep your eyes open.
Here are just a few amazing connections that scientists have found between sleep and avoiding getting sick …
Sleep deprivation suppresses your immune system, making you more susceptible to illness.
Ever notice that you’re especially prone to sniffling, sneezing, and other sickness when you don’t get enough ZZZs? It’s not in your head!
For example, being sleep deprived makes us more likely to catch a cold. In a 2009 study, people sleeping less than 7 hours per night had a 3 times greater risk of catching a cold than those with 8 hours or more.
A study from the University of Washington dug into the relationship between chronic sleep deprivation and the immune system. By examining 11 identical twins with different sleep patterns, researchers found that the twins who slept less had a more depressed immune system, compared with their siblings.
We all know that fatigue makes us more cranky and easily inflamed, but it actually undermines a key part of the body’s inflammatory response—called cytokines— absolutely essential for fighting off infections.
And, as exhaustion rises so does the risk of serious infection. In a study of 57,000 women, those trying to get by on less than 5 hours of sleep a night (pretty common for new parents) had a 50% increase in risk of pneumonia.
Sleep helps fight infection and boosts the immune system’s response to vaccinations.
While a lack of sleep potentially weakens your immune defenses, on the flip side, several studies have found that sleep promotes a stronger immune response to vaccines—which improves our body’s immunological memory!
Sleep may also help our T cells (basically the immune system’s attack dog that works specifically against viruses) better glom onto their target to fight the infection, according to a study out of Germany.
Bottom line: Sleep is one of the best things you can do to strengthen your immune system and protect your body from cold and flu…and potentially from more serious illness too!
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